| 01.04 | |  Dwars door Vlaanderen | 1.UWT | |
| 03.04 | |  Grand Prix Alanya | 1.2 | |
| 03.04 | |  La Route Adélie de Vitré | 1.1 | |
| 04.04 | |  NXT Classic | 1.1 | |
| 04.04 | |  Gran Premio Miguel Indurain | 1.Pro | |
| 04.04 | | Boucle de l'Artois | 1.2 | |
| 05.04 | | Ronde van Vlaanderen | 1.UWT | |
| 05.04 | |  National Road Championships - United Arab Emirates TT | CN | |
| 06.04 | 11.04 | Itzulia Basque Country | 2.UWT | |
| 06.04 | | Cholet Agglo Tour | 1.1 | |
| 07.04 | 10.04 | Région Pays de la Loire Tour | 2.Pro | |
| 08.04 | 12.04 | Circuit des Ardennes | 2.2 | |
| 08.04 | | Scheldeprijs | 1.Pro | |
| 09.04 | 12.04 | Tour of Mersin | 2.2 | |
| 09.04 | |  Oceania Road Championships TT | CC | |
| 10.04 | |  Giro Ciclistico della Città Metropolitana di Reggio Calabria | 1.1 | |
| 10.04 | | Oceania Road Championships | CC | |
| 11.04 | | HLC Omloop van de Braakman | 1.2 | |
| 12.04 | |  Ślężański Mnich - VeloBank Bruki & Szutry | 1.2 | |
| 12.04 | | Clasica de Pascua | 1.2 | |
| 12.04 | | National Road Championships - United Arab Emirates | CN | |
| 12.04 | | Paris-Roubaix | 1.UWT | |
| 14.04 | 18.04 | O Gran Camiño - The Historical Route | 2.1 | |
| 15.04 | 19.04 | Tour du Loir et Cher | 2.2 | |
| 15.04 | 19.04 |  Tour of Hainan | 2.Pro | |
| 15.04 | | Ronde van Limburg | 1.1 | |
| 17.04 | 19.04 |  Tour of Bosnia and Herzegovina | 2.2 | |
| 17.04 | 26.04 |  Tour d'Algérie | 2.2 | |
| 17.04 | | Classic Grand Besançon Doubs | 1.1 | |
| 17.04 | | De Brabantse Pijl | 1.Pro | |
| 18.04 | | Tour du Jura Cycliste | 1.1 | |
| 19.04 | | Tour du Doubs | 1.1 | Cancelled |
| 19.04 | | Amstel Gold Race | 1.UWT | |
| 20.04 | 21.04 |  Grand Prix Samarkand | 2.1 | |
| 20.04 | 24.04 | Tour of the Alps | 2.Pro | |
| 22.04 | | La Flèche Wallonne | 1.UWT | |
| 22.04 | 25.04 | Belgrade Banjaluka | 2.2 | |
| 23.04 | 26.04 | Vuelta Asturias Julio Alvarez Mendo | 2.1 | |
| 24.04 | |  National Road Championships - Egypt TT | CN | |
| 25.04 | 01.05 | Le Tour de Bretagne Cycliste | 2.2 | |
| 25.04 | | National Road Championships - Egypt | CN | |
| 26.04 | | Giro dell'Appennino | 1.1 | |
| 26.04 | | Liège-Bastogne-Liège | 1.UWT | |
| 26.04 | |  Rutland-Melton CiCLE Classic | 1.2 | |
| 26.04 | | Giro della Provincia di Biella - Torino-Biella | 1.2 | |
| 26.04 | 03.05 | Presidential Cycling Tour of Turkiye | 2.Pro | |
| 28.04 | | Grand Prix de la Ville d'Alger | 1.2 | |
| 28.04 | 03.05 |  Tour de Romandie | 2.UWT | |
| 28.04 | 29.04 | Tour of Bostonliq | 2.2 | |
| 29.04 | 03.05 |  Tour of the Gila Men | 2.2 | |
| 29.04 | 03.05 |  Vuelta Bantrab | 2.2 | |